Hydrochloric Acid → 6-[(6-Chloro-Pyridin-3-yl)-Hydroxy-(3-Methyl-3H-Imidazol-4-yl)-Methyl]-4-(3-Ethoxy-Phenyl)-1H-Quinolin-2-One

HRID 1123619Notes

Reaction equation

HRID 1123619 reaction equation
[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]([OH:9])([c:10]2[n:11]([CH3:15])[cH:12][n:13][cH:14]2)[c:16]2[cH:17][c:18]3[c:19](-[c:28]4[cH:29][c:30]([O:34][CH2:35][CH3:36])[cH:31][cH:32][cH:33]4)[cH:20][c:21]([O:26][CH3:27])[n:22][c:23]3[cH:24][cH:25]2)[cH:6][n:7]1.[ClH:37]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]([OH:9])([c:10]2[n:11]([CH3:15])[cH:12][n:13][cH:14]2)[c:16]2[cH:17][c:18]3[c:19](-[c:28]4[cH:29][c:30]([O:34][CH2:35][CH3:36])[cH:31][cH:32][cH:33]4)[cH:20][c:21](=[O:26])[nH:22][c:23]3[cH:24][cH:25]2)[cH:6][n:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 22465427(6-chloro-pyridin-3-yl)-[4-(3-ethoxy-phenyl)-2-methoxy-quinolin-6-yl]-(3-methyl-3H-imidazol-4-yl)-methanol

Product 1

HCID 224653976-[(6-Chloro-Pyridin-3-yl)-Hydroxy-(3-Methyl-3H-Imidazol-4-yl)-Methyl]-4-(3-Ethoxy-Phenyl)-1H-Quinolin-2-One

Sources & evidence

ORD record
ord-0a576ffce7384df9aea79680257ba9e2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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