Pyridine → N-(2-phenylpropan-2-yl)-3-[[2-(1H-pyrrole-2-carbonylamino)benzoyl]amino]-1H-furo[3,2-c]pyrazole-5-carboxamide

HRID 1123974Notes

Reaction equation

HRID 1123974 reaction equation
[CH2:54]([O:55][CH2:56][CH3:57])[CH3:58].[CH3:15][C:16]([CH3:17])([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[NH:24][C:25](=[O:26])[c:27]1[cH:28][c:29]2[nH:30][n:31][c:32]([NH:35][C:36]([c:37]3[c:38]([NH2:43])[cH:39][cH:40][cH:41][cH:42]3)=[O:44])[c:33]2[o:34]1.[Cl:51][CH2:52][Cl:53].[Cl:9][C:10]([C:11]([Cl:12])=[O:13])=[O:14].[O:59]=[CH:60][N:61]([CH3:62])[CH3:63].[cH:45]1[cH:46][cH:47][n:48][cH:49][cH:50]1.[nH:1]1[c:2]([C:6](=[O:7])[OH:8])[cH:3][cH:4][cH:5]1>>[nH:1]1[c:2]([C:6](=[O:8])[NH:43][c:38]2[c:37]([C:36]([NH:35][c:32]3[n:31][nH:30][c:29]4[cH:28][c:27]([C:25]([NH:24][C:16]([CH3:15])([CH3:17])[c:18]5[cH:19][cH:20][cH:21][cH:22][cH:23]5)=[O:26])[o:34][c:33]43)=[O:44])[cH:42][cH:41][cH:40][cH:39]2)[cH:3][cH:4][cH:5]1

Participants

8

Reactant 7

HCID 1049PyridineHCID 3283Diethyl EtherHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 12473Pyrrole-2-Carboxylic AcidHCID 65578Oxalyl chlorideHCID 578786473-(2-Amino-benzoylamino)-1H-furo[3,2-c]pyrazole-5-carboxylic acid (1-methyl-1-phenyl-ethyl)-amide

Product 1

HCID 23624279N-(2-phenylpropan-2-yl)-3-[[2-(1H-pyrrole-2-carbonylamino)benzoyl]amino]-1H-furo[3,2-c]pyrazole-5-carboxamide

Sources & evidence

ORD record
ord-a8e53099bb9544e7886c07147a59c9ca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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