Dichloromethane → 3-(4-Bromophenyl)-5-({[tert-butyl(dimethyl)silyl]oxy}methyl)-4,5-dihydroisoxazole

HRID 1124436Notes

Reaction equation

HRID 1124436 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:9][O:10][CH:11]([CH2:13][OH:14])[CH2:12]2)[cH:6][cH:7]1.[C:22]([CH3:23])([CH3:24])([CH3:25])[Si:26]([CH3:27])([CH3:28])[Cl:29].[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[CH3:33][N:34]([CH3:35])[c:36]1[cH:37][cH:38][n:39][cH:40][cH:41]1.[Cl:30][CH2:31][Cl:32]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:9][O:10][CH:11]([CH2:13][O:14][Si:26]([C:22]([CH3:23])([CH3:24])[CH3:25])([CH3:27])[CH3:28])[CH2:12]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 142844-(Dimethylamino)pyridineHCID 28928tert-Butyldimethylsilyl chlorideHCID 15888252[3-(4-Bromophenyl)-4,5-dihydro-1,2-oxazol-5-yl]methanol

Product 1

HCID 179544873-(4-Bromophenyl)-5-({[tert-butyl(dimethyl)silyl]oxy}methyl)-4,5-dihydroisoxazole

Sources & evidence

ORD record
ord-bd8a6fee073e46379472055e51e201ca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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