Pyridine → Ethanesulfonic acid[2-fluoro-3-(7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide

HRID 1124491Notes

Reaction equation

HRID 1124491 reaction equation
[CH2:30]([CH3:31])[S:32](=[O:33])(=[O:34])[Cl:35].[NH2:1][c:2]1[c:3]([F:19])[c:4]([C:8](=[O:9])[c:10]2[cH:11][nH:12][c:13]3[n:14][cH:15][n:16][cH:17][c:18]23)[cH:5][cH:6][cH:7]1.[O:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1.[S:25]([Cl:26])([Cl:27])(=[O:28])=[O:29].[cH:36]1[cH:37][cH:38][n:39][cH:40][cH:41]1>>[NH:1]([c:2]1[c:3]([F:19])[c:4]([C:8](=[O:9])[c:10]2[cH:11][nH:12][c:13]3[n:14][cH:15][n:16][cH:17][c:18]23)[cH:5][cH:6][cH:7]1)[S:32]([CH2:30][CH3:31])(=[O:33])=[O:34]

Participants

6

Reactant 5

HCID 1049PyridineHCID 8028TetrahydrofuranHCID 11667Ethanesulfonyl chlorideHCID 24648Sulfuryl chlorideHCID 57963256(3-amino-2-fluoro-phenyl)-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanone

Product 1

HCID 57963306Ethanesulfonic acid[2-fluoro-3-(7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide

Sources & evidence

ORD record
ord-9070b09488e24782812276091f8255f9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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