Dimethylformamide → 3-[5-Amino-4-(3-pyrazin-2-yl-benzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide
Reaction equation
[CH2:29]([Sn:30]([CH2:31][CH2:32][CH2:33][CH3:40])([c:34]1[n:35][cH:36][cH:37][n:38][cH:39]1)[CH2:41][CH2:42][CH2:43][CH3:44])[CH2:45][CH2:46][CH3:47].[NH2:1][c:2]1[c:3]([C:20]([c:21]2[cH:22][c:23]([I:27])[cH:24][cH:25][cH:26]2)=[O:28])[cH:4][n:5][n:6]1-[c:7]1[cH:8][c:9]([C:10](=[O:11])[NH:12][CH:13]2[CH2:14][CH2:15]2)[cH:16][cH:17][c:18]1[CH3:19].[O:48]=[CH:49][N:50]([CH3:51])[CH3:52].[Pd:53].[c:111]1([P:112]([c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)[c:119]2[cH:120][cH:121][cH:122][cH:123][cH:124]2)[cH:125][cH:126][cH:127][cH:128][cH:129]1.[c:54]1([P:55]([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[cH:68][cH:69][cH:70][cH:71][cH:72]1.[c:73]1([P:74]([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)[cH:87][cH:88][cH:89][cH:90][cH:91]1.[c:92]1([P:93]([c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)[c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)[cH:106][cH:107][cH:108][cH:109][cH:110]1>>[NH2:1][c:2]1[c:3]([C:20]([c:21]2[cH:22][c:23](-[c:34]3[n:35][cH:36][cH:37][n:38][cH:39]3)[cH:24][cH:25][cH:26]2)=[O:28])[cH:4][n:5][n:6]1-[c:7]1[cH:8][c:9]([C:10](=[O:11])[NH:12][CH:13]2[CH2:14][CH2:15]2)[cH:16][cH:17][c:18]1[CH3:19]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c8ad9259456c4fbe822736dc5968c8d3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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