Chloride → 3-Cyclohexyl-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one

HRID 1124768Notes

Reaction equation

HRID 1124768 reaction equation
[Br:1][c:2]1[c:3](=[O:20])[n:4](-[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:5][c:6](-[c:8]2[n:9][cH:10][cH:11][cH:12][cH:13]2)[cH:7]1.[CH:22]1([Mg+:28])[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]1.[Cl-:21].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1.[OH2:29]>>[c:2]1([CH:22]2[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]2)[c:3](=[O:20])[n:4](-[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:5][c:6](-[c:8]2[n:9][cH:10][cH:11][cH:12][cH:13]2)[cH:7]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 962WaterHCID 8028TetrahydrofuranHCID 223190653-Bromo-1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-oneHCID 178507034HCID 178507034, compound

Product 1

HCID 223192163-Cyclohexyl-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one

Sources & evidence

ORD record
ord-744d5382d9384dcba4eebd1147dbde61
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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