Trifluoroacetic acid → 3-Hydroxy-N-{[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-5-trifluoromethyl-benzamide
Reaction equation
[CH3:1][CH2:2][N:3]=[C:4]=[N:5][CH2:6][CH2:7][CH2:8][N:9]([CH3:10])[CH3:11].[F:33][C:34]([F:35])([F:36])[C:37]([OH:38])=[O:39].[NH2:12][CH2:13][C:14](=[O:15])[NH:16][CH:17]1[CH2:18][N:19]([CH:21]2[CH2:22][CH2:23][CH:24]([c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[CH2:25][CH2:26]2)[CH2:20]1.[OH:40][c:41]1[cH:42][c:43]([C:50]([F:51])([F:52])[F:53])[cH:44][c:45]([C:46](=[O:47])[OH:48])[cH:49]1>>[NH:12]([CH2:13][C:14](=[O:15])[NH:16][CH:17]1[CH2:18][N:19]([CH:21]2[CH2:22][CH2:23][CH:24]([c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[CH2:25][CH2:26]2)[CH2:20]1)[C:46]([c:45]1[cH:44][c:43]([C:50]([F:51])([F:52])[F:53])[cH:42][c:41]([OH:40])[cH:49]1)=[O:47]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-1516d694b4cd474e94797be60441d6cf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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