Water → N-[1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxopyrrolidin-3-yl]thieno[3,2-b]pyridine-2-sulfonamide
Reaction equation
[CH3:50][C:51]#[N:52].[CH:27]([N:28]([CH:29]([CH3:30])[CH3:31])[CH2:32][CH3:33])([CH3:34])[CH3:35].[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7].[NH2:8][CH:9]1[C:10](=[O:26])[N:11]([CH2:14][c:15]2[cH:16][cH:17][c:18]3[cH:19][cH:20][n:21][c:22]([NH2:25])[c:23]3[cH:24]2)[CH2:12][CH2:13]1.[OH2:49].[s:36]1[c:37]([S:45](=[O:46])(=[O:47])[Cl:48])[cH:38][c:39]2[n:40][cH:41][cH:42][cH:43][c:44]12>>[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7].[NH:8]([CH:9]1[C:10](=[O:26])[N:11]([CH2:14][c:15]2[cH:16][cH:17][c:18]3[cH:19][cH:20][n:21][c:22]([NH2:25])[c:23]3[cH:24]2)[CH2:12][CH2:13]1)[S:45]([c:37]1[s:36][c:44]2[c:39]([cH:38]1)[n:40][cH:41][cH:42][cH:43]2)(=[O:46])=[O:47]Participants
8
Reactant 6
Product 2
Sources & evidence
- ORD record
- ord-dd99e1d1c558442db1de6b6bf01cb937
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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