Pyridine → 3-{[4-Chloro-5-fluoro-2-(methoxymethoxy)benzoyl]amino}thiophene-2-carboxamide
Reaction equation
[Cl:6][c:7]1[cH:8][c:9]([O:17][CH2:18][O:19][CH3:20])[c:10]([C:11](=[O:12])[O-:13])[cH:14][c:15]1[F:16].[Li+:21].[NH2:22][c:23]1[c:24]([C:28](=[O:29])[NH2:30])[s:25][cH:26][cH:27]1.[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5].[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[Cl:6][c:7]1[cH:8][c:9]([O:17][CH2:18][O:19][CH3:20])[c:10]([C:11](=[O:13])[NH:22][c:23]2[c:24]([C:28](=[O:29])[NH2:30])[s:25][cH:26][cH:27]2)[cH:14][c:15]1[F:16]Participants
6
Sources & evidence
- ORD record
- ord-d25e5b22a3a94e5cafb1d62e8559fabd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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