Water → N-(4-(Dipropylphosphoryl)phenyl)-2-isopropyl-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine
Reaction equation
[CH2:5]([CH2:6][CH3:7])[P:8](=[O:9])([CH2:10][CH2:11][CH3:12])[c:13]1[cH:14][cH:15][c:16]([NH:19][c:20]2[c:21]3[n:22][cH:23][n:24]([CH:30]4[O:31][CH2:32][CH2:33][CH2:34][CH2:35]4)[c:25]3[n:26][c:27]([I:29])[n:28]2)[cH:17][cH:18]1.[CH:1]([CH3:2])([CH3:3])[I:4].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41].[OH2:36].[Pd:43]([Cl:44])[Cl:45].[Zn:42].[c:46]1([P:47]([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[cH:60][cH:61][cH:62][cH:63][cH:64]1.[c:65]1([P:66]([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[cH:79][cH:80][cH:81][cH:82][cH:83]1>>[CH:1]([CH3:2])([CH3:3])[c:27]1[n:26][c:25]2[c:21]([c:20]([NH:19][c:16]3[cH:15][cH:14][c:13]([P:8]([CH2:5][CH2:6][CH3:7])(=[O:9])[CH2:10][CH2:11][CH3:12])[cH:18][cH:17]3)[n:28]1)[n:22][cH:23][n:24]2[CH:30]1[O:31][CH2:32][CH2:33][CH2:34][CH2:35]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-c57f62758ed04e77835bbac77994126c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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