Phenol → Ethyl 2-Phenoxy-4-Trifluoromethyl-5-Oxazolecarboxylate

HRID 1126972Notes

Reaction equation

HRID 1126972 reaction equation
[Cl:1][c:2]1[o:3][c:4]([C:11](=[O:12])[O:13][CH2:14][CH3:15])[c:5]([C:7]([F:8])([F:9])[F:10])[n:6]1.[Na:23].[O:24]=[CH:25][N:26]([CH3:27])[CH3:28].[c:16]1([OH:22])[cH:17][cH:18][cH:19][cH:20][cH:21]1>>[c:2]1([O:22][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[o:3][c:4]([C:11](=[O:12])[O:13][CH2:14][CH3:15])[c:5]([C:7]([F:8])([F:9])[F:10])[n:6]1

Participants

5

Reactant 4

HCID 996PhenolHCID 6228DimethylformamideHCID 5360545SodiumHCID 12785855Ethyl 2-chloro-4-(trifluoromethyl)oxazole-5-carboxylate

Product 1

HCID 12785857Ethyl 2-Phenoxy-4-Trifluoromethyl-5-Oxazolecarboxylate

Sources & evidence

ORD record
ord-3b1da41da30a43d0b74d358031459794
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…