Water → N-(2-fluoro-4-chloro-5-cyclopentyloxyphenyl)-3,4,5,6-tetrahydrophthalimide

HRID 1127017Notes

Reaction equation

HRID 1127017 reaction equation
[C:16]1(=[O:26])[C:17]2=[C:18]([C:19](=[O:20])[O:21]1)[CH2:22][CH2:23][CH2:24][CH2:25]2.[CH3:28][CH2:29][O:30][C:31](=[O:32])[CH3:33].[Cl:1][c:2]1[cH:3][c:4]([F:15])[c:5]([NH2:6])[cH:7][c:8]1[O:9][CH:10]1[CH2:11][CH2:12][CH2:13][CH2:14]1.[OH2:27]>>[Cl:1][c:2]1[cH:3][c:4]([F:15])[c:5]([N:6]2[C:16](=[O:21])[C:17]3=[C:18]([C:19]2=[O:20])[CH2:22][CH2:23][CH2:24][CH2:25]3)[cH:7][c:8]1[O:9][CH:10]1[CH2:11][CH2:12][CH2:13][CH2:14]1

Participants

5

Reactant 4

HCID 962WaterHCID 8857Ethyl AcetateHCID 124753,4,5,6-Tetrahydrophthalic anhydrideHCID 152793894-Chloro-5-(cyclopentyloxy)-2-fluorobenzenamine

Product 1

HCID 15279390N-(2-fluoro-4-chloro-5-cyclopentyloxyphenyl)-3,4,5,6-tetrahydrophthalimide

Sources & evidence

ORD record
ord-77d3bb77062a471f84e03b2fb8e05cbd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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