Dichloromethane → (3S,4R)-Methyl 1-(tert-butyl)-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylate
Reaction equation
[CH3:22][O:23][CH2:24][N:25]([C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:30][Si:31]([CH3:32])([CH3:33])[CH3:34].[Cl:15][c:16]1[cH:17][cH:18][n:19][cH:20][n:21]1.[Cl:42][CH2:43][Cl:44].[F:1][c:2]1[c:3]([CH:9]=[CH:10][C:11](=[O:12])[O:13][CH3:14])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[OH:35][C:36]([C:37]([F:38])([F:39])[F:40])=[O:41]>>[F:1][c:2]1[c:3]([CH:9]2[CH:10]([C:11](=[O:12])[O:13][CH3:14])[CH2:24][N:25]([C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:30]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-bc8487729f624cb380095815a86e57fa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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