Methanol → 7-bromo-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H-1,4-benzodiazepin-1-acetic acid methyl ester
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[C:7]([c:13]1[n:14][cH:15][cH:16][cH:17][cH:18]1)=[N:8][CH2:9][C:10](=[O:12])[NH:11]2.[Br:28][CH2:29][C:30](=[O:31])[O:32][CH3:33].[CH2:34]([Cl:35])[Cl:36].[CH3:20][O-:21].[CH3:23][N:24]([CH3:25])[CH:26]=[O:27].[CH3:37][OH:38].[CH3:40][c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1.[Na+:22].[OH2:39]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[C:7]([c:13]1[n:14][cH:15][cH:16][cH:17][cH:18]1)=[N:8][CH2:9][C:10](=[O:12])[N:11]2[CH2:29][C:30](=[O:31])[O:32][CH3:33]Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-aec5d347ae764173bf4ba023d26913e2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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