Hydrochloric Acid → HCID 67187050, compound

HRID 1127525Notes

Reaction equation

HRID 1127525 reaction equation
[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[Cl:21][C:22]([Cl:23])=[O:24].[Cl:51][CH2:52][Cl:53].[ClH:25].[ClH:26].[F:1][C:2]1([F:14])[C:3]2([CH2:4]1)[CH2:5][CH2:6][NH:7][c:8]1[cH:9][cH:10][cH:11][cH:12][c:13]12.[NH:27]1[CH2:28][CH:29]([c:32]2[cH:33][n:34][nH:35][cH:36]2)[CH2:30][CH2:31]1.[cH:15]1[cH:16][cH:17][n:18][cH:19][cH:20]1>>[F:1][C:2]1([F:14])[C:3]2([CH2:4]1)[CH2:5][CH2:6][N:7]([C:22](=[O:24])[N:27]1[CH2:28][CH:29]([c:32]3[cH:33][n:34][nH:35][cH:36]3)[CH2:30][CH2:31]1)[c:8]1[cH:9][cH:10][cH:11][cH:12][c:13]12

Participants

9

Reactant 8

HCID 313Hydrochloric Acid2×HCID 1049PyridineHCID 1140TolueneHCID 6344DichloromethaneHCID 6371PhosgeneHCID 8471TriethylamineHCID 67187230HCID 67187230, compoundHCID 671885982,2-difluoro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-quinoline]

Product 1

HCID 67187050HCID 67187050, compound

Sources & evidence

ORD record
ord-848d732f4aca46998d7614decd76038e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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