Dimethylformamide → 1-{2-[4-(4-Hydroxy-4-methyl-piperidin-1-ylmethyl)-phenyl]-ethyl}-4-(pyridin-2-ylmethoxy)-1H-pyridin-2-one
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][n:11]2[c:12](=[O:25])[cH:13][c:14]([O:17][CH2:18][c:19]3[n:20][cH:21][cH:22][cH:23][cH:24]3)[cH:15][cH:16]2)[cH:7][cH:8]1.[CH2:34]([N:35]([CH:36]([CH3:37])[CH3:38])[CH:39]([CH3:40])[CH3:41])[CH3:42].[O:43]=[CH:44][N:45]([CH3:46])[CH3:47].[OH:26][C:27]1([CH3:33])[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]1>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][n:11]2[c:12](=[O:25])[cH:13][c:14]([O:17][CH2:18][c:19]3[n:20][cH:21][cH:22][cH:23][cH:24]3)[cH:15][cH:16]2)[cH:7][cH:8]1)[N:30]1[CH2:29][CH2:28][C:27]([OH:26])([CH3:33])[CH2:32][CH2:31]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-fdbe908160274c5a8286da05e07a3a8b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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