Tetrahydrofuran → 4-(2-(trans-(4-(3-Methoxypropyl)-4-silacyclohexyl))ethyl)-4'-(3,4-difluorophenyl)biphenyl
Reaction equation
[CH2:74]1[O:75][CH2:76][CH2:77][CH2:78]1.[CH3:1][O:2][CH2:3][CH2:4][CH2:5][SiH:6]1[CH2:7][CH2:8][CH:9]([CH2:12][CH2:13][c:14]2[cH:15][cH:16][c:17]([Br:20])[cH:18][cH:19]2)[CH2:10][CH2:11]1.[Cl:22][c:23]1[cH:24][cH:25][c:26](-[c:29]2[cH:30][c:31]([F:36])[c:32]([F:35])[cH:33][cH:34]2)[cH:27][cH:28]1.[Mg:21].[Ni:37]([Cl:38])[Cl:39].[c:40]1([PH:41][CH2:42][CH2:43][CH2:44][PH:45][c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[cH:52][cH:53][cH:54][cH:55][cH:56]1.[c:57]1([PH:58][CH2:59][CH2:60][CH2:61][PH:62][c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[cH:69][cH:70][cH:71][cH:72][cH:73]1>>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][SiH:6]1[CH2:7][CH2:8][CH:9]([CH2:12][CH2:13][c:14]2[cH:15][cH:16][c:17](-[c:23]3[cH:24][cH:25][c:26](-[c:29]4[cH:30][c:31]([F:36])[c:32]([F:35])[cH:33][cH:34]4)[cH:27][cH:28]3)[cH:18][cH:19]2)[CH2:10][CH2:11]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-68a8042b5b3d4e76b69f161d2687f28e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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