Hydrochloric Acid → N-(2-methyl-7-(4-ureidopiperidin-1-yl)pyrazolo[1,5-a]pyrimidin-5-yl)-2-(pyridin-4-yl)cyclopropanecarboxamide

HRID 1127654Notes

Reaction equation

HRID 1127654 reaction equation
[CH3:35][N:36]1[CH2:37][CH2:38][CH2:39][C:40]1=[O:41].[CH3:42][S:43]([CH3:44])=[O:45].[CH3:46][OH:47].[Cl:1][c:2]1[cH:3][c:4]([NH:12][C:13](=[O:14])[CH:15]2[CH:16]([c:18]3[cH:19][cH:20][n:21][cH:22][cH:23]3)[CH2:17]2)[n:5][c:6]2[n:7]1[n:8][c:9]([CH3:11])[cH:10]2.[ClH:24].[NH:25]1[CH2:26][CH2:27][CH:28]([NH:31][C:32](=[O:33])[NH2:34])[CH2:29][CH2:30]1>>[c:2]1([N:25]2[CH2:26][CH2:27][CH:28]([NH:31][C:32](=[O:33])[NH2:34])[CH2:29][CH2:30]2)[cH:3][c:4]([NH:12][C:13](=[O:14])[CH:15]2[CH:16]([c:18]3[cH:19][cH:20][n:21][cH:22][cH:23]3)[CH2:17]2)[n:5][c:6]2[n:7]1[n:8][c:9]([CH3:11])[cH:10]2

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 679Dimethyl SulfoxideHCID 887MethanolHCID 13387N-methyl-2-pyrrolidoneHCID 126317214-(Aminocarbonyl)aminopiperidineHCID 86652285HCID 86652285, compound

Product 1

HCID 67064441N-(2-methyl-7-(4-ureidopiperidin-1-yl)pyrazolo[1,5-a]pyrimidin-5-yl)-2-(pyridin-4-yl)cyclopropanecarboxamide

Sources & evidence

ORD record
ord-25b6cddf3a8246bcb77493f3004ec299
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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