proline dl-form → HCID 178430397, compound

HRID 1128297Notes

Reaction equation

HRID 1128297 reaction equation
[Br:21][c:22]1[c:23]([N:28]2[CH2:29][CH2:30][CH:31]([NH:34][c:35]3[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]3)[CH2:32][CH2:33]2)[n:24][cH:25][cH:26][cH:27]1.[C:42](=[O:43])([O-:44])[O-:45].[CH3:1][CH:2]1[N:3]([C:15]([C:16]([F:17])([F:18])[F:19])=[O:20])[CH:4]([CH3:14])[CH2:5][N:6]([CH2:8][c:9]2[n:10][nH:11][cH:12][cH:13]2)[CH2:7]1.[CH3:56][S:57]([CH3:58])=[O:59].[Cu:60][I:61].[K+:46].[K+:47].[OH:48][C:49]([CH:50]1[NH:51][CH2:52][CH2:53][CH2:54]1)=[O:55]>>[CH3:1][CH:2]1[N:3]([C:15]([C:16]([F:17])([F:18])[F:19])=[O:20])[CH:4]([CH3:14])[CH2:5][N:6]([CH2:8][c:9]2[n:10][n:11](-[c:22]3[c:23]([N:28]4[CH2:29][CH2:30][CH:31]([NH:34][c:35]5[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]5)[CH2:32][CH2:33]4)[n:24][cH:25][cH:26][cH:27]3)[cH:12][cH:13]2)[CH2:7]1

Participants

8

Reactant 7

HCID 614proline dl-formHCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 672469241-(3-Bromo-2-pyridinyl)-N-(4-fluorophenyl)-4-piperidinamineHCID 178430411HCID 178430411, compound

Product 1

HCID 178430397HCID 178430397, compound

Sources & evidence

ORD record
ord-5b85fd0ba2d2418d9fc1c2f90d6a9a21
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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