Diethyl Ether → 7-methyl-3-phenyl-2,3-dihydro-4H-1,4-benzoxazin-4-amine

HRID 1128429Notes

Reaction equation

HRID 1128429 reaction equation
[Al+3:2].[CH2:26]([O:27][CH2:28][CH3:29])[CH3:30].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41].[CH3:7][c:8]1[cH:9][c:10]2[c:11]([cH:24][cH:25]1)[N:12]([N:22]=[O:23])[CH:13]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[CH2:14][O:15]2.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[CH3:7][c:8]1[cH:9][c:10]2[c:11]([cH:24][cH:25]1)[N:12]([NH2:22])[CH:13]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[CH2:14][O:15]2

Participants

8

Reactant 7

HCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 8058HexaneHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 223363397-methyl4-nitroso-3-phenyl-3,4-dihydro-2H-1,4-benzoxazine

Product 1

HCID 223363427-methyl-3-phenyl-2,3-dihydro-4H-1,4-benzoxazin-4-amine

Sources & evidence

ORD record
ord-7cf4ddb0c76b4fd28c67df357fb24954
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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