Acetonitrile → tert-butyl N-[3-[[7-fluoro-1-(2-fluoroethyl)-2-oxo-3H-indol-5-yl]amino]-2-hydroxypropyl]carbamate
Reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21]([NH:22][CH2:23][CH:24]1[O:25][CH2:26]1)=[O:27].[CH3:37][C:38]#[N:39].[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45].[F:28][C:29]([F:30])([F:31])[S:32]([O-:33])(=[O:34])=[O:35].[Li+:36].[NH2:1][c:2]1[cH:3][c:4]2[c:8]([c:9]([F:11])[cH:10]1)[N:7]([CH2:12][CH2:13][F:14])[C:6](=[O:15])[CH2:5]2>>[NH:1]([c:2]1[cH:3][c:4]2[c:8]([c:9]([F:11])[cH:10]1)[N:7]([CH2:12][CH2:13][F:14])[C:6](=[O:15])[CH2:5]2)[CH2:26][CH:24]([CH2:23][NH:22][C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:27])[OH:25]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-0ecc0bfe163d41eeaf5874f75e81865c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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