Hydroxide → 3-amino-N-methyl-6-[3-({[(3-morpholin-4-ylphenyl)methyl]amino}methyl) phenyl]pyrazine-2-carboxamide
Reaction equation
[F:55][C:56]([F:57])([F:58])[C:59]([OH:60])=[O:61].[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:12]2[cH:13][c:14]([C:15]([OH:16])=[O:17])[cH:18][cH:19][cH:20]2)[n:6][c:7]1[C:8](=[O:9])[NH:10][CH3:11].[O:62]1[CH2:63][CH2:64][N:65]([c:68]2[cH:69][c:70]([CH2:74][NH2:75])[cH:71][cH:72][cH:73]2)[CH2:66][CH2:67]1.[O:77]=[CH:78][N:79]([CH3:80])[CH3:81].[OH-:76].[OH:21][n:22]1[c:23]2[c:24]([cH:25][cH:26][cH:27][cH:28]2)[n:29][n:30]1.[P-:31]([F:32])([F:33])([F:34])([F:35])([F:36])[F:37].[n:38]1([O:39][C:40]([N:41]([CH3:42])[CH3:43])=[N+:44]([CH3:45])[CH3:46])[c:47]2[cH:48][cH:49][cH:50][cH:51][c:52]2[n:53][n:54]1>>[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:12]2[cH:13][c:14]([CH2:15][NH:75][CH2:74][c:70]3[cH:69][c:68]([N:65]4[CH2:64][CH2:63][O:62][CH2:67][CH2:66]4)[cH:73][cH:72][cH:71]3)[cH:18][cH:19][cH:20]2)[n:6][c:7]1[C:8](=[O:9])[NH:10][CH3:11]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-fb825f369e234e73af29a1d2c5b3506d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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