HRID1128615

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID16028

Tetrabutylammonium

C16H36N+

HCID30165

Iodide ion

I-

HCID81531

Diisopropylethylamine

C8H19N

HCID56923688

未命名化合物

结构：CNCC(O[Si](C)(C)C(C)(C)C)c1ccc(O)c2[nH]c(=O)ccc12

HCID66988440

未命名化合物

PRODUCTS

生成物

结构：CN(CCCC#Cc1ccc(NC(=O)C(F)(F)F)cc1)CC(O[Si](C)(C)C(C)(C)C)c1ccc(O)c2[nH]c(=O)ccc12

HCID87226557

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c0dde9c2c8f249a7925beded05827a13
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (7/10)

反应 SMILES

[Br:1][CH2:2][CH2:3][CH2:4][C:5]#[C:6][c:7]1[cH:8][cH:9][c:10]([NH:13][C:14]([C:15]([F:16])([F:17])[F:18])=[O:19])[cH:11][cH:12]1.[C:20]([CH3:21])([CH3:22])([CH3:23])[Si:24]([O:25][CH:26]([CH2:27][NH:28][CH3:29])[c:30]1[c:31]2[cH:32][cH:33][c:34](=[O:41])[nH:35][c:36]2[c:37]([OH:40])[cH:38][cH:39]1)([CH3:42])[CH3:43].[CH2:59]([N+:60]([CH2:61][CH2:62][CH2:63][CH3:64])([CH2:65][CH2:66][CH2:67][CH3:68])[CH2:69][CH2:70][CH2:71][CH3:72])[CH2:73][CH2:74][CH3:75].[CH:44]([N:45]([CH2:46][CH3:47])[CH:48]([CH3:49])[CH3:50])([CH3:51])[CH3:52].[I-:58].[O:53]=[CH:54][N:55]([CH3:56])[CH3:57]>>[CH2:2]([CH2:3][CH2:4][C:5]#[C:6][c:7]1[cH:8][cH:9][c:10]([NH:13][C:14]([C:15]([F:16])([F:17])[F:18])=[O:19])[cH:11][cH:12]1)[N:28]([CH2:27][CH:26]([O:25][Si:24]([C:20]([CH3:21])([CH3:22])[CH3:23])([CH3:42])[CH3:43])[c:30]1[c:31]2[cH:32][cH:33][c:34](=[O:41])[nH:35][c:36]2[c:37]([OH:40])[cH:38][cH:39]1)[CH3:29]