3-Hydroxybenzaldehyde → 3-[(2,4,6-Trimethyl-benzylamino)-methyl]-phenol

HRID 1128764Notes

Reaction equation

HRID 1128764 reaction equation
[BH4-:21].[CH3:10][c:11]1[c:12]([CH2:13][NH2:14])[c:15]([CH3:20])[cH:16][c:17]([CH3:19])[cH:18]1.[CH3:29][OH:30].[ClH:23].[Na+:22].[Na+:28].[O-:24][C:25]([OH:26])=[O:27].[OH:1][c:2]1[cH:3][c:4]([CH:5]=[O:6])[cH:7][cH:8][cH:9]1>>[OH:1][c:2]1[cH:3][c:4]([CH2:5][NH:14][CH2:13][c:12]2[c:11]([CH3:10])[cH:18][c:17]([CH3:19])[cH:16][c:15]2[CH3:20])[cH:7][cH:8][cH:9]1

Participants

8

Reactant 7

HCID 1013-HydroxybenzaldehydeHCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ion2×HCID 28123BorohydrideHCID 4584332,4,6-Trimethylbenzylamine

Product 1

HCID 689821863-[(2,4,6-Trimethyl-benzylamino)-methyl]-phenol

Sources & evidence

ORD record
ord-119d4dd0a23a4d5680b6430db068a83a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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