Tetrahydrofuran → 2-Chloro-8-(1-isopropylpiperidin-4-yloxy)quinazoline
Reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[Cl:30][c:31]1[n:32][c:33]2[c:34]([OH:41])[cH:35][cH:36][cH:37][c:38]2[cH:39][n:40]1.[OH:20][CH:21]1[CH2:22][CH2:23][N:24]([CH:27]([CH3:28])[CH3:29])[CH2:25][CH2:26]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[O:20]([CH:21]1[CH2:22][CH2:23][N:24]([CH:27]([CH3:28])[CH3:29])[CH2:25][CH2:26]1)[c:34]1[c:33]2[n:32][c:31]([Cl:30])[n:40][cH:39][c:38]2[cH:37][cH:36][cH:35]1Participants
5
Sources & evidence
- ORD record
- ord-b0a21f3dbf534c7597fee277680fe589
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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