Hydrochloric Acid → Hydrochloric Acid

HRID 1129465Notes

Reaction equation

HRID 1129465 reaction equation
[CH2:38]([Cl:39])[Cl:40].[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6](=[O:36])[n:7]([CH2:28][O:29][C:30]([C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH2:14][CH:15]1[CH2:16][CH2:17][N:18]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:19][CH2:20]1.[CH:41]([OH:42])([CH3:43])[CH3:44].[ClH:37]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6](=[O:36])[n:7]([CH2:28][O:29][C:30]([C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH2:14][CH:15]1[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]1.[ClH:37]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 3776IsopropanolHCID 6344DichloromethaneHCID 11733854tert-Butyl 4-(((6-methoxy-4-oxo-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-7-yl)oxy)methyl)piperidine-1-carboxylate

Product 2

HCID 313Hydrochloric AcidHCID 11058522(6-Methoxy-4-oxo-7-(piperidin-4-ylmethoxy)quinazolin-3(4H)-yl)methyl pivalate

Sources & evidence

ORD record
ord-9b8866267e644583a0e1e58482f28c58
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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