Sulfuric Acid → 1-(cyclopropylmethyl)-2-(4-ethoxybenzyl)-N-methyl-1H-benzimidazol-5-amine

HRID 112970Notes

Reaction equation

HRID 112970 reaction equation
[Al+3:36].[AlH3:29].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:1][N:2]([C:3](=[O:4])[O-:5])[c:6]1[cH:7][c:8]2[c:9]([n:10]([CH2:23][CH:24]3[CH2:25][CH2:26]3)[c:11]([CH2:13][c:14]3[cH:15][cH:16][c:17]([O:20][CH2:21][CH3:22])[cH:18][cH:19]3)[n:12]2)[cH:27][cH:28]1.[H-:35].[H-:38].[H-:39].[H-:40].[Li+:37].[S:30](=[O:31])(=[O:32])([OH:33])[OH:34]>>[CH3:1][NH:2][c:6]1[cH:7][c:8]2[c:9]([n:10]([CH2:23][CH:24]3[CH2:25][CH2:26]3)[c:11]([CH2:13][c:14]3[cH:15][cH:16][c:17]([O:20][CH2:21][CH3:22])[cH:18][cH:19]3)[n:12]2)[cH:27][cH:28]1

Participants

8

Reactant 7

HCID 1118Sulfuric AcidHCID 8028Tetrahydrofuran2×HCID 14488Aluminum hydrideHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 178466236HCID 178466236, compound

Product 1

HCID 221812881-(cyclopropylmethyl)-2-(4-ethoxybenzyl)-N-methyl-1H-benzimidazol-5-amine

Sources & evidence

ORD record
ord-1942bb9999004621877000fdd6177404
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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