HRID1130384

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID8471

Triethylamine

C6H15N

HCID588081

2,4-Difluorobenzoyl chloride

C7H3ClF2O

结构：COc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1N

HCID18314537

未命名化合物

PRODUCTS

生成物

结构：COc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1NC(=O)c1ccc(F)cc1F

HCID18314540

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-41ccd96d84e54cd7ab5545a828f2b3b9
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (7/10)

反应 SMILES

[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[F:32][c:33]1[c:34]([C:35](=[O:36])[Cl:37])[cH:38][cH:39][c:40]([F:42])[cH:41]1.[NH2:1][c:2]1[c:3](-[n:12]2[c:13](=[O:24])[n:14]([CH3:23])[c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][c:17]2=[O:18])[c:4]([F:11])[cH:5][c:6]([Cl:10])[c:7]1[O:8][CH3:9].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1>>[NH:1]([c:2]1[c:3](-[n:12]2[c:13](=[O:24])[n:14]([CH3:23])[c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][c:17]2=[O:18])[c:4]([F:11])[cH:5][c:6]([Cl:10])[c:7]1[O:8][CH3:9])[C:35]([c:34]1[c:33]([F:32])[cH:41][c:40]([F:42])[cH:39][cH:38]1)=[O:36]