Tetrahydrofuran → 7-(4-methoxybenzyl)-4-hydroxy-3-(hydroxymethyl)-1,7-naphthyridin-8(7H)-one
Reaction equation
[Al+3:28].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][n:8]2[cH:9][cH:10][c:11]3[c:12]([OH:24])[c:13]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[cH:14][n:15][c:16]3[c:17]2=[O:18])[cH:25][cH:26]1.[H-:27].[H-:30].[H-:31].[H-:32].[Li+:29]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][n:8]2[cH:9][cH:10][c:11]3[c:12]([OH:24])[c:13]([CH2:19][OH:20])[cH:14][n:15][c:16]3[c:17]2=[O:18])[cH:25][cH:26]1Participants
6
Sources & evidence
- ORD record
- ord-7528d2fe9a954441b225410af19d7347
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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