Chloride → 6-[3-(3,4-Difluoro-phenyl)-5-formyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester
Reaction equation
[CH2:54]([N+:55]([CH2:56][CH3:57])([CH2:58][CH3:59])[CH2:60][CH3:61])[c:62]1[cH:63][cH:64][cH:65][cH:66][cH:67]1.[CH3:1][O:2][C:3]([c:4]1[cH:5][n:6][c:7]([O:10][CH2:11][c:12]2[c:13](-[c:25]3[cH:26][c:27]([F:32])[c:28]([F:31])[cH:29][cH:30]3)[n:14][o:15][c:16]2[CH:17]=[CH:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:8][cH:9]1)=[O:33].[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45].[CH3:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH3:52].[Cl-:53].[I+3:34]([O-:35])([O-:36])([O-:37])[O-:38].[Na+:39].[O:68]1[CH2:69][CH2:70][O:71][CH2:72][CH2:73]1.[OH2:74].[Os:75](=[O:76])(=[O:77])(=[O:78])=[O:79]>>[CH3:1][O:2][C:3]([c:4]1[cH:5][n:6][c:7]([O:10][CH2:11][c:12]2[c:13](-[c:25]3[cH:26][c:27]([F:32])[c:28]([F:31])[cH:29][cH:30]3)[n:14][o:15][c:16]2[CH:17]=[O:35])[cH:8][cH:9]1)=[O:33]Participants
11
Reactant 10
Product 1
Sources & evidence
- ORD record
- ord-49c8284f12fe49598f7b988beba0a36f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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