Dimethylformamide → N-(2,3-dimethyl-1H-indol-5-yl)-6-methoxy-7-(4-pyrrolidin-1-ylbut-2-enoxy)quinazolin-4-amine
Reaction equation
[CH3:13][c:14]1[nH:15][c:16]2[cH:17][cH:18][c:19]([NH:24][c:25]3[n:26][cH:27][n:28][c:29]4[cH:30][c:31]([OH:37])[c:32]([O:35][CH3:36])[cH:33][c:34]34)[cH:20][c:21]2[c:22]1[CH3:23].[Cl:72][CH2:73][Cl:74].[N:57]1([CH2:62][CH:63]=[CH:64][CH2:65][OH:66])[CH2:58][CH2:59][CH2:60][CH2:61]1.[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[O:67]=[CH:68][N:69]([CH3:70])[CH3:71].[c:38]1([P:39]([c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[cH:52][cH:53][cH:54][cH:55][cH:56]1>>[CH3:13][c:14]1[nH:15][c:16]2[cH:17][cH:18][c:19]([NH:24][c:25]3[n:26][cH:27][n:28][c:29]4[cH:30][c:31]([O:37][CH2:65][CH:64]=[CH:63][CH2:62][N:57]5[CH2:58][CH2:59][CH2:60][CH2:61]5)[c:32]([O:35][CH3:36])[cH:33][c:34]34)[cH:20][c:21]2[c:22]1[CH3:23]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-46dd602396bc4ad48887ce66d800507f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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