Tetrahydrofuran → 1-Benzyl-4-[N-methyl-N-(3-(cyclopropylamino)-2-pyridinyl)amino]piperidine
Reaction equation
[Al+3:30].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([c:15]2[n:16][cH:17][cH:18][cH:19][c:20]2[NH:21][C:22]2([O:25][CH2:26][CH3:27])[CH2:23][CH2:24]2)[CH3:28])[CH2:12][CH2:13]1.[H-:29].[H-:32].[H-:33].[H-:34].[Li+:31].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([c:15]2[n:16][cH:17][cH:18][cH:19][c:20]2[NH:21][CH:22]2[CH2:23][CH2:24]2)[CH3:28])[CH2:12][CH2:13]1Participants
6
Sources & evidence
- ORD record
- ord-dfca915ba07f4c4495dd72d0e8751ee5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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