Dichloromethane → 4-Chloro-6-fluoroquinazoline

HRID 1132012Notes

Reaction equation

HRID 1132012 reaction equation
[CH2:25]([Cl:26])[Cl:27].[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[F:1][c:2]1[cH:3][c:4]2[c:5]([OH:12])[n:6][cH:7][n:8][c:9]2[cH:10][cH:11]1.[P:13]([Cl:14])([Cl:15])([Cl:16])=[O:17]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([Cl:15])[n:6][cH:7][n:8][c:9]2[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 24813Phosphorus oxychlorideHCID 178518010HCID 178518010, compound

Product 1

HCID 130594574-Chloro-6-fluoroquinazoline

Sources & evidence

ORD record
ord-527acede58684cf4a18038a05f564981
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…