Dimethylformamide → 3,4-dimethoxyphenyl 2-[(2-aminophenyl)carbamoyl]-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate

HRID 1132330Notes

Reaction equation

HRID 1132330 reaction equation
[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[N+:20]([c:21]1[cH:22][cH:23][c:24]([O:29][C:30](=[O:25])[O:31][c:32]2[cH:33][c:34]([O:40][CH3:41])[c:35]([O:38][CH3:39])[cH:36][cH:37]2)[cH:26][cH:27]1)([O-:28])=[O:42].[NH2:1][c:2]1[c:3]([NH:8][C:9](=[O:10])[c:11]2[cH:12][c:13]3[c:18]([s:19]2)[CH2:17][CH2:16][NH:15][CH2:14]3)[cH:4][cH:5][cH:6][cH:7]1.[O:50]=[CH:51][N:52]([CH3:53])[CH3:54]>>[NH2:1][c:2]1[c:3]([NH:8][C:9](=[O:10])[c:11]2[cH:12][c:13]3[c:18]([s:19]2)[CH2:17][CH2:16][N:15]([C:30](=[O:29])[O:31][c:32]2[cH:33][c:34]([O:40][CH3:41])[c:35]([O:38][CH3:39])[cH:36][cH:37]2)[CH2:14]3)[cH:4][cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 44203072Carbonic acid 3,4-dimethoxy-phenyl ester 4-nitro-phenyl esterHCID 58117019N-(2-aminophenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-carboxamide

Product 1

HCID 252301123,4-dimethoxyphenyl 2-[(2-aminophenyl)carbamoyl]-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate

Sources & evidence

ORD record
ord-b4d1e04c2ddf4ec6bdbcf24d5cbd60b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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