Water → {1-[6-(3,4-Difluoro-phenoxy)-4-pyrimidin-2-yl-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-2,2-dimethyl-propyl}-carbamic acid benzyl ester
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([NH:10][CH:11]([C:12]([CH3:13])([CH3:14])[CH3:15])[C:16](=[O:17])[N:18]1[CH:19]2[CH:20]([CH2:21][CH2:22]1)[NH:23][CH2:24][CH:25]2[O:26][c:27]1[cH:28][c:29]([F:34])[c:30]([F:33])[cH:31][cH:32]1)=[O:35].[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:45][c:46]1[n:47][cH:48][cH:49][cH:50][n:51]1.[O:52]=[CH:53][N:54]([CH3:55])[CH3:56].[OH2:57]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([NH:10][CH:11]([C:12]([CH3:13])([CH3:14])[CH3:15])[C:16](=[O:17])[N:18]1[CH:19]2[CH:20]([CH2:21][CH2:22]1)[N:23]([c:46]1[n:47][cH:48][cH:49][cH:50][n:51]1)[CH2:24][CH:25]2[O:26][c:27]1[cH:28][c:29]([F:34])[c:30]([F:33])[cH:31][cH:32]1)=[O:35]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a072131abfaa4c4e8b1ba315eeb3d0f0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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