HRID1132564

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID813

Potassium cation

K+

2 次

HCID962

Water

H2O

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID11776

Triphenylphosphine

C18H15P

4 次

HCID19660

Carbonate

CO3-2

HCID23938

Palladium

HCID285645

4-Fluorophenylboronic acid

C6H6BFO2

HCID10749704

3-amino-6-chloropicolinamide

C6H6ClN3O

PRODUCTS

生成物

HCID59647906

3-Amino-6-(4-fluorophenyl)pyridine-2-carboxamide

C12H10FN3O

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fa884ff521fb4d05afe101ea8005c717
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (7/10)

反应 SMILES

[C:12](=[O:13])([O-:14])[O-:15].[K+:16].[K+:17].[NH2:1][c:2]1[c:3]([C:9](=[O:10])[NH2:11])[n:4][c:5]([Cl:8])[cH:6][cH:7]1.[O:28]=[CH:29][N:30]([CH3:31])[CH3:32].[OH2:33].[OH:18][B:19]([OH:20])[c:21]1[cH:22][cH:23][c:24]([F:25])[cH:26][cH:27]1.[Pd:34].[c:35]1([P:36]([c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[cH:49][cH:50][cH:51][cH:52][cH:53]1.[c:54]1([P:55]([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[cH:68][cH:69][cH:70][cH:71][cH:72]1.[c:73]1([P:74]([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)[cH:87][cH:88][cH:89][cH:90][cH:91]1.[c:92]1([P:93]([c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)[c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)[cH:106][cH:107][cH:108][cH:109][cH:110]1>>[NH2:1][c:2]1[c:3]([C:9](=[O:10])[NH2:11])[n:4][c:5](-[c:21]2[cH:22][cH:23][c:24]([F:25])[cH:26][cH:27]2)[cH:6][cH:7]1