Dimethylformamide → 3,4-dimethoxyphenyl 2-[(2-aminophenyl)carbamoyl]-1-methyl-1,4,5,7-tetrahydro-6H-pyrrolo[2,3-c]pyridine-6-carboxylate

HRID 1132828Notes

Reaction equation

HRID 1132828 reaction equation
[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[N+:28]([c:29]1[cH:30][cH:31][c:32]([O:37][C:38](=[O:33])[O:39][c:40]2[cH:41][c:42]([O:48][CH3:49])[c:43]([O:46][CH3:47])[cH:44][cH:45]2)[cH:34][cH:35]1)([O-:36])=[O:50].[NH2:1][c:2]1[c:3]([NH:8][C:9](=[O:10])[c:11]2[cH:12][c:13]3[c:14]([n:19]2[CH3:20])[CH2:15][NH:16][CH2:17][CH2:18]3)[cH:4][cH:5][cH:6][cH:7]1.[O:51]=[CH:52][N:53]([CH3:54])[CH3:55]>>[NH2:1][c:2]1[c:3]([NH:8][C:9](=[O:10])[c:11]2[cH:12][c:13]3[c:14]([n:19]2[CH3:20])[CH2:15][N:16]([C:38](=[O:37])[O:39][c:40]2[cH:41][c:42]([O:48][CH3:49])[c:43]([O:46][CH3:47])[cH:44][cH:45]2)[CH2:17][CH2:18]3)[cH:4][cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 44203072Carbonic acid 3,4-dimethoxy-phenyl ester 4-nitro-phenyl esterHCID 66864727N-(2-aminophenyl)-1-methyl-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

Product 1

HCID 668652443,4-dimethoxyphenyl 2-[(2-aminophenyl)carbamoyl]-1-methyl-1,4,5,7-tetrahydro-6H-pyrrolo[2,3-c]pyridine-6-carboxylate

Sources & evidence

ORD record
ord-88fac7b21f194333915c4570f55ed943
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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