Tetrahydrofuran → 2,6-Difluoro-N-(1-{[4-iodo-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)benzamide
Reaction equation
[Br:27][CH2:28][c:29]1[c:30]([C:36]([F:37])([F:38])[F:39])[cH:31][c:32]([I:35])[cH:33][cH:34]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:17][Si:18]([N-:19][Si:20]([CH3:21])([CH3:22])[CH3:23])([CH3:24])[CH3:25].[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[n:8][nH:9][cH:10][cH:11]2)[c:12]([F:16])[cH:13][cH:14][cH:15]1.[Li+:26]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[n:8][n:9]([CH2:28][c:29]3[c:30]([C:36]([F:37])([F:38])[F:39])[cH:31][c:32]([I:35])[cH:33][cH:34]3)[cH:10][cH:11]2)[c:12]([F:16])[cH:13][cH:14][cH:15]1Participants
6
Sources & evidence
- ORD record
- ord-f8c7611097c543a9b3a84e51127815a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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