Tetrahydrofuran → 4-(4-Fluorophenyl)-3-formylpiperidine-6-one
Reaction equation
[C:10]([CH2:11][CH2:14][CH:15]1[CH2:16][NH:17][C:18](=[O:28])[CH2:19][CH:20]1[c:21]1[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]1)([OH:12])=[O:13].[CH3:1][CH:2]([CH2:3][AlH:4][CH2:5][CH:6]([CH3:7])[CH3:8])[CH3:9].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[CH:14]([CH:15]1[CH2:16][NH:17][C:18](=[O:28])[CH2:19][CH:20]1[c:21]1[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]1)=[O:29]Participants
4
Sources & evidence
- ORD record
- ord-eed0dcb960b0480e925b90e6ac2f75b9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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