Dimethyl Sulfone → 1-[6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3H-benzoimidazol-5-yl]-2-methanesulfonyl-ethanol
Reaction equation
[Br:22][c:23]1[cH:24][c:25]([Cl:42])[c:26]([NH:29][c:30]2[c:31]([CH:40]=[O:41])[cH:32][c:33]3[c:34]([n:35][cH:36][nH:37]3)[c:38]2[F:39])[cH:27][cH:28]1.[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:11][N:12]([CH3:13])[P:14]([N:15]([CH3:16])[CH3:17])([N:18]([CH3:19])[CH3:20])=[O:21].[CH3:1][S:2](=[O:3])(=[O:4])[CH3:5].[CH3:6][CH2:7][CH2:8][CH2:9][Li:10]>>[CH2:1]([S:2](=[O:3])(=[O:4])[CH3:5])[CH:40]([c:31]1[c:30]([NH:29][c:26]2[c:25]([Cl:42])[cH:24][c:23]([Br:22])[cH:28][cH:27]2)[c:38]([F:39])[c:34]2[c:33]([cH:32]1)[nH:37][cH:36][n:35]2)[OH:41]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-277320b2a7064f8eaaf8dee9af029f9e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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