Tetrahydrofuran → 3-{4-[2-(4-Chloro-phenyl)-7-oxo-4,7-dihydro-5H-thieno[2,3-c]pyridin-6-yl]-2-methoxy-phenoxy}-azetidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([O:12][c:13]2[c:14]([O:37][CH3:38])[cH:15][c:16]([NH:19][C:20](=[O:21])[c:22]3[s:23][c:24](-[c:30]4[cH:31][cH:32][c:33]([Cl:36])[cH:34][cH:35]4)[cH:25][c:26]3[CH2:27][CH2:28][OH:29])[cH:17][cH:18]2)[CH2:11]1.[CH2:39]([P:40]([CH2:41][CH2:42][CH2:43][CH3:44])[CH2:45][CH2:46][CH2:47][CH3:48])[CH2:49][CH2:50][CH3:51].[O:52]=[C:53]([O:54][CH:55]([CH3:56])[CH3:57])[N:58]=[N:59][C:60]([O:61][CH:62]([CH3:63])[CH3:64])=[O:65].[O:66]1[CH2:67][CH2:68][CH2:69][CH2:70]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([O:12][c:13]2[c:14]([O:37][CH3:38])[cH:15][c:16]([N:19]3[C:20](=[O:21])[c:22]4[s:23][c:24](-[c:30]5[cH:31][cH:32][c:33]([Cl:36])[cH:34][cH:35]5)[cH:25][c:26]4[CH2:27][CH2:28]3)[cH:17][cH:18]2)[CH2:11]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-a782a3c389a64638b059595be2ae96be
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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