Dimethylformamide → 1-(tert-Butoxycarbonyl)-4-[4-methyl-2-(4-pyridyl)-5-thiazolecarbonyl]piperazine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[CH3:14][c:15]1[n:16][c:17](-[c:23]2[cH:24][cH:25][n:26][cH:27][cH:28]2)[s:18][c:19]1[C:20](=[O:21])[OH:22].[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[O:46]=[CH:47][N:48]([CH3:49])[CH3:50].[OH:36][n:37]1[c:38]2[c:39]([cH:40][cH:41][cH:42][cH:43]2)[n:44][n:45]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([C:20]([c:19]2[c:15]([CH3:14])[n:16][c:17](-[c:23]3[cH:24][cH:25][n:26][cH:27][cH:28]3)[s:18]2)=[O:21])[CH2:12][CH2:13]1Participants
6
Sources & evidence
- ORD record
- ord-57a1646bb78147a5a775b84e207bb17d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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