Methanol → 5-chloro-4-(8-(cyclopentyloxy)-7-methoxy-2-oxo-2H-chromen-4-ylamino)nicotinic acid
Reaction equation
[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:34][OH:35].[Cl:3][c:4]1[cH:5][n:6][cH:7][c:8]([C:9](=[O:10])[O:11][CH3:12])[c:13]1[NH:14][c:15]1[cH:16][c:17](=[O:33])[o:18][c:19]2[c:20]([O:27][CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32]3)[c:21]([O:25][CH3:26])[cH:22][cH:23][c:24]12.[Li+:1].[OH-:2]>>[Cl:3][c:4]1[cH:5][n:6][cH:7][c:8]([C:9](=[O:10])[OH:11])[c:13]1[NH:14][c:15]1[cH:16][c:17](=[O:33])[o:18][c:19]2[c:20]([O:27][CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32]3)[c:21]([O:25][CH3:26])[cH:22][cH:23][c:24]12Participants
6
Sources & evidence
- ORD record
- ord-53ab32924ea643c6b60f86a9e4f4dc48
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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