Acetate → 2-(5-Bromothiazol-2-yl)propane-2-sulfonamide

HRID 1135294Notes

Reaction equation

HRID 1135294 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([C:7]([CH3:8])([CH3:9])[S:10](=[O:11])(=[O:12])[CH2:13][CH2:14][C:15]([O:16][CH3:17])=[O:18])[s:6]1.[C:22]([O-:23])(=[O:24])[CH3:25].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:19][O-:20].[NH2:27][O:28][S:29]([OH:30])(=[O:31])=[O:32].[Na+:21].[Na+:26].[OH2:38]>>[Br:1][c:2]1[cH:3][n:4][c:5]([C:7]([CH3:8])([CH3:9])[S:10](=[O:11])(=[O:12])[NH2:27])[s:6]1

Participants

8

Reactant 7

HCID 175AcetateHCID 923Sodium ion2×HCID 962WaterHCID 8028TetrahydrofuranHCID 76284hydroxylamine-O-sulfonic acidHCID 3826051MethoxideHCID 67258095Methyl 3-{[2-(5-bromo-1,3-thiazol-2-yl)propan-2-yl]sulfonyl}propanoate

Product 1

HCID 672570342-(5-Bromothiazol-2-yl)propane-2-sulfonamide

Sources & evidence

ORD record
ord-541d7504a7a444c5bdbc54355ddee54c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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