Benzaldehyde → Methyl 2-(1-oxopropyl)-3-(4-fluorophenyl)-4-phenyl-4-oxobutanoate

HRID 1136027Notes

Reaction equation

HRID 1136027 reaction equation
[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:33][CH2:34][OH:35].[CH3:37][n+:38]1[c:39]([CH3:40])[c:41]([CH2:42][CH2:43][OH:44])[s:45][cH:46]1.[CH:18](=[O:19])[c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1.[Cl:47][CH2:48][Cl:49].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:6]=[C:7]([C:8](=[O:9])[O:10][CH3:11])[C:12]([CH2:13][CH3:14])=[O:15])[cH:16][cH:17]1.[I-:36]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:6]([CH:7]([C:8](=[O:9])[O:10][CH3:11])[C:12]([CH2:13][CH3:14])=[O:15])[C:18](=[O:19])[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:16][cH:17]1

Participants

8

Reactant 7

HCID 240BenzaldehydeHCID 702EthanolHCID 6344DichloromethaneHCID 8471TriethylamineHCID 30165Iodide IonHCID 3420026Thiazolium, 5-(2-hydroxyethyl)-3,4-dimethyl-HCID 53755005Methyl 2-(4-fluorobenzylidene)-3-oxopentanoate

Product 1

HCID 23047461Methyl 2-(1-oxopropyl)-3-(4-fluorophenyl)-4-phenyl-4-oxobutanoate

Sources & evidence

ORD record
ord-5644d7e94d194cbba65b2f24c1ec2bea
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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