Dimethylformamide → 1-{[3-(3-Chloro-4-methoxyphenyl)isoxazol-4-yl]carbonyl}-5-methyl-3-phenylpyrrolidin-3-ol
Reaction equation
[B-:27]([F:28])([F:29])([F:30])[F:31].[CH2:18]([N:19]([CH:20]([CH3:21])[CH3:22])[CH:23]([CH3:24])[CH3:25])[CH3:26].[CH3:49][CH:50]1[CH2:51][C:52]([OH:55])([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[CH2:53][NH:54]1.[Cl:1][c:2]1[cH:3][c:4](-[c:10]2[n:11][o:12][cH:13][c:14]2[C:15](=[O:16])[OH:17])[cH:5][cH:6][c:7]1[O:8][CH3:9].[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[n:32]1([O:33][C:34]([N:35]([CH3:36])[CH3:37])=[N+:38]([CH3:39])[CH3:40])[c:41]2[cH:42][cH:43][cH:44][cH:45][c:46]2[n:47][n:48]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:10]2[n:11][o:12][cH:13][c:14]2[C:15](=[O:17])[N:54]2[CH:50]([CH3:49])[CH2:51][C:52]([OH:55])([c:56]3[cH:57][cH:58][cH:59][cH:60][cH:61]3)[CH2:53]2)[cH:5][cH:6][c:7]1[O:8][CH3:9]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-c8fddec43e924311ad45ebe3dae02ca0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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