Chloroform → 2-(5,6,7,8-Tetrahydroimidazo[1,2-a]pyrazin-7-yl)-4-(3-chloro-4-methoxybenzylamino)-5-ethoxycarbonylpyrimidine

HRID 1136101Notes

Reaction equation

HRID 1136101 reaction equation
[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[CH3:44][CH2:45][O:46][C:47](=[O:48])[CH3:49].[CH:40]([Cl:41])([Cl:42])[Cl:43].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[c:6]([NH:8][CH2:9][c:10]2[cH:11][c:12]([Cl:18])[c:13]([O:16][CH3:17])[cH:14][cH:15]2)[n:7]1.[n:24]1[cH:25][cH:26][n:27]2[c:28]1[CH2:29][NH:30][CH2:31][CH2:32]2>>[c:2]1([N:30]2[CH2:29][c:28]3[n:24][cH:25][cH:26][n:27]3[CH2:32][CH2:31]2)[n:3][cH:4][c:5]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[c:6]([NH:8][CH2:9][c:10]2[cH:11][c:12]([Cl:18])[c:13]([O:16][CH3:17])[cH:14][cH:15]2)[n:7]1

Participants

6

Reactant 5

HCID 6212ChloroformHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 132470465,6,7,8-Tetrahydroimidazo(1,2-a)pyrazineHCID 226655812-Chloro-4-(3-chloro-4-methoxybenzylamino)-5-ethoxycarbonylpyrimidine

Product 1

HCID 226655882-(5,6,7,8-Tetrahydroimidazo[1,2-a]pyrazin-7-yl)-4-(3-chloro-4-methoxybenzylamino)-5-ethoxycarbonylpyrimidine

Sources & evidence

ORD record
ord-a808262e90c94bffa2ffddbb35e35b74
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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