Dimethylformamide → {4-[3-(2-Chloro-pyrimidin-4-yloxy)-phenoxymethyl]-benzyl}carbamic acid tert-butyl ester
Reaction equation
[C:16](=[O:17])([O-:18])[O-:19].[C:22]([CH3:23])([CH3:24])([CH3:25])[O:26][C:27]([NH:28][CH2:29][c:30]1[cH:31][cH:32][c:33]([CH2:36][Cl:37])[cH:34][cH:35]1)=[O:38].[CH2:51]([N+:52]([CH2:53][CH2:54][CH2:55][CH3:56])([CH2:57][CH2:58][CH2:59][CH3:60])[CH2:61][CH2:62][CH2:63][CH3:64])[CH2:65][CH2:66][CH3:67].[CH3:39][CH2:40][O:41][C:42]([CH3:43])=[O:44].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][cH:14]2)[n:7]1.[Cs+:20].[Cs+:21].[I-:50].[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]([O:15][CH2:36][c:33]3[cH:32][cH:31][c:30]([CH2:29][NH:28][C:27]([O:26][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:38])[cH:35][cH:34]3)[cH:12][cH:13][cH:14]2)[n:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-d3975519e35949b8b073b01069833f3c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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