Dimethylformamide → Methyl 4-fluoro-2-(6-nitropyridin-3-yloxy)benzoate

HRID 1137407Notes

Reaction equation

HRID 1137407 reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[CH3:29][N:30]([CH3:31])[CH:32]=[O:33].[CH3:34][CH2:35][O:36][C:37](=[O:38])[CH3:39].[Cs+:27].[Cs+:28].[F:1][c:2]1[cH:3][c:4]([OH:12])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[N+:13](=[O:14])([O-:15])[c:16]1[n:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]1>>[F:1][c:2]1[cH:3][c:4]([O:12][c:19]2[cH:18][n:17][c:16]([N+:13](=[O:14])[O-:15])[cH:21][cH:20]2)[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 2598065-Chloro-2-nitropyridineHCID 2775386Methyl 4-fluorosalicylate

Product 1

HCID 67226297Methyl 4-fluoro-2-(6-nitropyridin-3-yloxy)benzoate

Sources & evidence

ORD record
ord-57ddd839fcf7469ab86bbc6832cc7d3a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…