Tetrahydrofuran → Methyl 4-[1-(4-pyridyl)piperidin-4-yl]oxyphenoxyacetate

HRID 1137789Notes

Reaction equation

HRID 1137789 reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[OH:14][c:15]1[cH:16][cH:17][c:18]([O:19][CH2:20][C:21](=[O:22])[O:23][CH3:24])[cH:25][cH:26]1.[c:27]1([P:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:41][cH:42][cH:43][cH:44][cH:45]1.[n:1]1[cH:2][cH:3][c:4]([N:7]2[CH2:8][CH2:9][CH:10]([OH:13])[CH2:11][CH2:12]2)[cH:5][cH:6]1>>[n:1]1[cH:2][cH:3][c:4]([N:7]2[CH2:8][CH2:9][CH:10]([O:13][c:15]3[cH:16][cH:17][c:18]([O:19][CH2:20][C:21](=[O:22])[O:23][CH3:24])[cH:25][cH:26]3)[CH2:11][CH2:12]2)[cH:5][cH:6]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 602731Methyl 2-(4-hydroxyphenoxy)acetateHCID 234476191-(Pyridin-4-yl)piperidin-4-ol

Product 1

HCID 18918626Methyl 4-[1-(4-pyridyl)piperidin-4-yl]oxyphenoxyacetate

Sources & evidence

ORD record
ord-19f94d2bab7c465aa496b8672bdd2820
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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